Increased gene expression of a facilitated diffusion urea transporter in the skin of the African lungfish (Protopterus annectens) during massively elevated post-terrestrialization urea excretion
نویسندگان
چکیده
منابع مشابه
Increased gene expression of a facilitated diffusion urea transporter in the skin of the African lungfish (Protopterus annectens) during massively elevated post-terrestrialization urea excretion.
The full-length cDNA sequence of a putative urea transporter (lfUT) of the facilitated diffusion UT-A type has been cloned from the African lungfish Protopterus annectens. The lfUT cDNA is 1990 bp in length and its open reading frame encodes a 409 amino acid long protein, with a calculated molecular mass of 44,723 Da. The sequence is closest to those of amphibians ( approximately 65% amino acid...
متن کاملOrnithine-Urea Cycle Enzymes in the African Lungfish, Protopterus aethiopicus.
The presence of all five enzymes of the ornithine-urea cycle has been demonstrated in the liver of the African lungfish Protopterus aethiopicus. Levels of activity of the rate-limiting enzymes, carbamoyl phosphate synthetase and argininosuccinate synthetase, are similar to those in the premetamorphic tadpole of Rana catesbeiana and considerably lower than the levels reported for other ureotelic...
متن کاملAestivation and brain of the African lungfish Protopterus annectens
Scientists have long been fascinated by animals undergoing aestivation, a state of torpor at high temperature, due to its great potential in fields ranging from medicine to space travel. The brain of the African lungfish is able to coordinate a whole-body response to induce aestivation and to arouse from aestivation.
متن کاملAestivation Induces Changes in the mRNA Expression Levels and Protein Abundance of Two Isoforms of Urea Transporters in the Gills of the African Lungfish, Protopterus annectens
The African lungfish, Protopterus annectens, is ammonotelic in water despite being ureogenic. When it aestivates in mucus cocoon on land, ammonia is detoxified to urea. During the maintenance phase of aestivation, urea accumulates in the body, which is subsequently excreted upon arousal. Urea excretion involves urea transporters (UT/Ut). This study aimed to clone and sequence the ut isoforms fr...
متن کاملHaematological changes in African lungfish, Protopterus annectens after aerial exposure.
Specimens of the west African lungfish, Protopterus annectens (mean weight 294.3 g mean length 38.1 cm), procured from Agulu lake at Agulu in Anambra state, Nigeria were removed from the ambient water and exposed to complete aerial life for a period of seven consecutive days after which some of their haematological changes were determined. There were significant polycythaemia, leucocytosis, thr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Experimental Biology
سال: 2009
ISSN: 1477-9145,0022-0949
DOI: 10.1242/jeb.025239